Top 10 COVID-19 Vaccines in the World

Top 10 COVID-19 Vaccines in the World

Scientifically, a vaccine is a suspension of dead, impoverished, or particles of pathogens or viruses or immunoglobulins or lymphocytes delivered to prevent disease. In simple words, a vaccine is a biological preparation that stimulates immunity of the body over certain diseases. And, Vaccines have provided relief towards various deadly pandemics over the decades. Currently, everyone is living with one such pandemic is “NOVEL CORONA VIRUS”.

Coronavirus is most probably called COVID-19 or nCoV means the novel coronavirus discovered in 2019. From 2019 till now, this deadly virus has entered into three waves of destruction with numerous mutating forms regularly. Corona is an infectious disease and spreads from the droplets of saliva, sneezing, cough, close contact with the infected, etc. Corona is affecting globally from every continent to every country and every age group, by preferring the comprised immune bodies first. It is taking new forms like alpha, beta, gamma, and delta rapidly that it is becoming more difficult to contain this pandemic. So, the WHO and all Health Ministries have decided to put an end to this fatal monster with a solution of vaccines. 

The most important and worth doing a thing to control any disease is to get complete knowledge about its transmission and to start following it on our own. For Corona, there are only three simple steps to control it:-

  1. Always mask on,
  2. Sanitizing hands frequently, and 
  3. Keeping a safe distance with everyone.

Although this will not cure the disease surely it will provide great help in stopping the chain of the virus to spread further. 

A vaccine’s general function is to trigger the body’s immune system against the disease-causing agents to generate antibodies. World Health Organization and many companies are working day and night to prepare an effective vaccine for Coronavirus. Vaccine preparation takes a very long time to come into action; from extraction to preparation to phase trials, to clinical trials, to human trials, and finally to action. Vaccines work efficiently towards the disease. The main aim of vaccines is not only to trigger the immune system but also to store some of the antibodies produced during the first vaccination as memory cells so that the body is always ready to fight for the next attack and not waiting for the vaccine to take action. There are so many vaccines prepared, some are under process across the globe of which the top 10 most efficient vaccines for COVID-19 are listed below;

  1. Comirnaty BNT162b2.
  2. Moderna Covid-19 Vaccine mRNA-1273.
  3. Covid-19 Vaccine AstraZeneca (AZD 1222).
  4. Sputnik V Vaccine.
  5. Sputnik Light.
  6. CoronaVac.
  7. EpiVacCorona.
  8. Covaxin (BBV152).
  9. CoviVac.
  10. Soberana 02.

The top 10 vaccines for COVID-19 are described below: 

1. Comirnaty BNT162b2:

Comirnaty BNT162b2 - Top 10 COVID-19 Vaccines in the World

Comirnaty initially named BNT 162b2 is the first Vaccine prepared by modifying the mRNA’s nucleoside. It has been developed multi-nationally by companies of Pfizer, and BioNTech whereas Fosun Pharma has given license to Comirnaty in China.

DOSAGE:- Comirnaty Vaccine is administered in two doses with 21 days between the doses.

EFFICIENCY:- The readings printed in the NEJM disclosed that the Moderna and Pfizer Vaccines have approximately 91% of efficiency towards the fully vaccinated and 81% efficiency for partially vaccinated.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Albania
  2. Andorra
  3. Argentina
  4. Aruba
  5. Australia
  6. Bahrain
  7. Bangladesh
  8. Bosnia and Herzegovina
  9. Brazil
  10. Brunei
  11. Canada
  12. Caribbean
  13. Chile
  14. Colombia
  15. Costa Rica
  16. Ecuador
  17. European Union
  18. Faroe Islands
  19. Greenland
  20. Hong Kong
  21. Iceland
  22. India
  23. Iraq
  24. Israel
  25. Japan
  26. Jordan
  27. Kuwait
  28. Lebanon
  29. Liechtenstein
  30. Macao
  31. Malaysia
  32. Maldives
  33. Mexico
  34. Moldova
  35. Monaco
  36. Mongolia
  37. New Zealand
  38. North Macedonia
  39. Norway
  40. Oman
  41. Palestine
  42. Pakistan
  43. Panama
  44. Peru
  45. Philippines
  46. Qatar
  47. Rwanda
  48. Saint Vincent and the Grenadines
  49. Saudi Arabia
  50. Serbia
  51. Singapore
  52. South Africa
  53. South Korea
  54. Sri Lanka
  55. Suriname
  56. Switzerland
  57. Thailand
  58. Tunisia
  59. Turkey
  60. Ukraine
  61. UAE
  62. UK
  63. US (16 and older)
  64. Vatican City
  65. Vietnam

This Vaccine is delivered intra-muscularly which means deep inside the muscles for rapid absorption of injection. The function of this Vaccine is to trigger the immune response towards the SARS-CoV-2 by mutating a full spike protein of the virus.

The common side effects of the Comirnaty Vaccine:

  • Pain or swelling at the injection site,
  • tiredness,
  • headache,
  • muscle pain,
  • fever and chills, and joint pain.

The less common side effects are:

  • redness at the injection site,
  • nausea,
  • enlarged lymph nodes,
  • feeling unwell,
  • pain in the limb,
  • insomnia,
  • Itching at the injection site.

2. Moderna Covid-19 Vaccine mRNA-1273:

Moderna Covid-19 Vaccine mRNA-1273 - Top 10 COVID-19 Vaccines in the World

Moderna COVID-19 Vaccine, formerly called mRNA -1273. It was manufactured by Moderna, BARDA, and NIAID based on the findings of associated coronaviruses. The other names of this vaccine are; Elasomeran in Australia, TAK-919 in Japan, and Spikevax in Europe.

DOSAGE:- Moderna Vaccine is a two doses vaccine injected within a gap of 28 days apart.

EFFICIENCY:- The evaluations published in the CDC’s MMWR displayed that the Moderna Vaccine is 80% efficient after the 14 days of first shot and 91% efficient after the 14 days of second shot.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Andorra
  2. Australia
  3. Bangladesh
  4. Brazil
  5. Botswana
  6. Canada
  7. Colombia
  8. European Union
  9. Faroe Islands
  10. Greenland
  11. Guatemala
  12. Honduras
  13. Iceland
  14. India
  15. Indonesia
  16. Israel
  17. Japan
  18. Liechtenstein
  19. Maldives
  20. Moldova
  21. Mongolia
  22. Norway
  23. Palestine
  24. Philippines
  25. Qatar
  26. Saint Vincent and the Grenadines
  27. Singapore
  28. South Korea
  29. Switzerland
  30. Taiwan
  31. Thailand
  32. United Kingdom
  33. UAE
  34. United States
  35. Vietnam

The most common side effects of Moderna Vaccine are as follows:

  • Pain,
  • swelling, or redness at the injection site,
  • Tiredness,
  • Headache,
  • Muscle or joint aches,
  • Chills,
  • Nausea and vomiting,
  • Underarm swelling,
  • Fever.

3. Covid-19 Vaccine AstraZeneca (AZD 1222): also known as Vaxzevira and Covishield:

Covid-19 Vaccine AstraZeneca (AZD 1222) also known as Vaxzevira and Covishield - Top 10 COVID-19 Vaccines in the World

COVID-19 Vaccine Astra-Zeneca is produced at the University of Oxford by the Astra-Zeneca and the Oxford Vaccine Group using a Chimpanzee’s adenovirus. In India, this Vaccine is often produced mutually by the Serum Institute of India and Astra-Zeneca and further sold by the name of Covishield.

DOSAGE:- Covishield injected in two doses with a gap of 4-12 weeks, and the antibody generation starts after the second or third booster dose of 46 weeks apart.

EFFICIENCY:- According to the data from the studies of the Botucatu in Brazil, the AstraZeneca Vaccine showed 71 % efficacy in symptomatic cases after the first dose.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Afghanistan
  2. Albania
  3. Algeria
  4. Andorra
  5. Angola
  6. Argentina
  7. Armenia
  8. Australia
  9. Bahamas
  10. Bahrain
  11. Bangladesh
  12. Barbados
  13. Bhutan
  14. Bolivia
  15. Botswana
  16. Brazil
  17. Brunei
  18. Cabo Verde
  19. Cambodia
  20. Canada
  21. Cambodia
  22. Caribbean
  23. Chile
  24. Colombia
  25. Congo
  26. Costa Rica
  27. Djibouti
  28. Dominican Republic
  29. Ecuador
  30. El Salvador
  31. Egypt
  32. Estonia
  33. Eswatani
  34. Ethiopia
  35. European Union
  36. Faroe Islands
  37. Fiji
  38. Gambia
  39. Georgia
  40. Ghana
  41. Greenland
  42. Guatemala
  43. Guinea-Bissau
  44. Guyana
  45. Honduras
  46. Hungary (SII)
  47. Iceland
  48. India
  49. Indonesia
  50. Iran
  51. Iraq
  52. Ivory Coast
  53. Japan
  54. Jordan
  55. Kenya
  56. Kosovo
  57. Kuwait
  58. Lebanon
  59. Lesotho
  60. Liberia
  61. Libya
  62. Malawi
  63. Malaysia
  64. Maldives
  65. Mali
  66. Mauritius
  67. Mexico
  68. Moldova
  69. Mongolia
  70. Morocco
  71. Myanmar
  72. Namibia
  73. Nepal
  74. Nicaragua
  75. Nigeria
  76. North Macedonia
  77. Norway
  78. Oman
  79. Pakistan
  80. Palestine
  81. Panama
  82. Papua New Guinea
  83. Peru
  84. Philippines
  85. Rwanda
  86. Saint Vincent and the Grenadines
  87. Samoa
  88. Serbia
  89. Seychelles
  90. Sierra Leone
  91. Somalia
  92. South Korea
  93. South Sudan
  94. Sri Lanka
  95. Sudan
  96. Suriname
  97. Taiwan
  98. Tajikistan
  99. Thailand
  100. Timor Leste
  101. Tonga, Togo
  102. Tuvalu
  103. Uganda
  104. Ukraine
  105. UK
  106. Uzbekistan
  107. Vietnam
  108. WHO (Oxford; SII/SK)
  109. Yemen
  110. Zambia.

The most common side effects of the Astra-Zeneca Vaccine are as follows:

  • Pain or tenderness at the injection site,
  • Headache,
  • Tiredness,
  • Muscle or joint aches,
  • Fever,
  • Chills,
  • Nausea.

4. Sputnik V Vaccine:

Sputnik V Vaccine was developed in Russia in the Gamaleya Research Institute and the Health Ministry of the Russian Federation. It was manufactured using a heterological recombinant adenovirus (rAd26 and rAd5), which was formerly called Gam-COVID-Vac).

DOSAGE:- Sputnik V is delivered in two doses with 21 days of the gap; however, the gap can be of 3 months also as prescribed by the Gamaleya representative.

EFFICIENCY:- The records published in the Lancet showed that the Sputnik V vaccine is 91.6% efficient based on the phase 3 trials results of 21,977 candidates.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Albania
  2. Algeria
  3. Angola
  4. Antigua and Barbuda
  5. Argentina
  6. Armenia
  7. Azerbaijan
  8. Bahrain
  9. Bangladesh
  10. Belarus
  11. Bolivia
  12. Brazil
  13. Congo
  14. Djibouti
  15. Ecuador
  16. Egypt
  17. Gabon
  18. Ghana
  19. Guatemala
  20. Guinea
  21. Guyana
  22. Honduras
  23. Hungary
  24. India
  25. Iran
  26. Iraq
  27. Jordan
  28. Kazakhstan
  29. Kenya
  30. Kyrgyzstan
  31. Laos
  32. Lebanon
  33. Maldives
  34. Mali
  35. Mexico
  36. Moldova
  37. Mongolia
  38. Montenegro
  39. Morocco
  40. Myanmar
  41. Namibia
  42. Nicaragua
  43. North Macedonia
  44. Pakistan
  45. Palestine
  46. Panama
  47. Paraguay
  48. Republika Srpska
  49. Russia (Sputnik Light)
  50. Saint Vincent and the Grenadines
  51. San Marino
  52. Serbia
  53. Slovakia
  54. Sri Lanka
  55. Syria
  56. Tunisia
  57. Turkey
  58. Turkmenistan
  59. United Arab Emirates
  60. Uzbekistan
  61. Venezuela
  62. Zimbabwe.

The most common side effects of Sputnik V are as follows:

  • Flu-like illness,
  • headache,
  • fatigue,
  • Injection-site reactions. 

5. Sputnik Light:

Sputnik Light - Top 10 COVID-19 Vaccines in the World

Sputnik Light Vaccine has been developed in Russia by the Gamaleya Research Institute and the Health Ministry of the Russian Federation. It was manufactured using a heterological recombinant adenovirus and is the first component to use the Ad26 vector of Gamaleya’s Sputnik V Vaccine.

DOSAGE:- Sputnik Light is first single-dose Vaccine administered only in a single shot and it can also be given as a third booster dose for the Sputnik V patients.

EFFICIENCY:- According to the records of the Gamaleya, the Sputnik Light Vaccine is 79.4 % efficient.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Angola
  2. Bahrain
  3. Congo
  4. Kyrgyzstan
  5. Mauritius
  6. Mongolia
  7. Nicaragua
  8. Palestine
  9. Russia
  10. Venezuela.

The side effects of Sputnik Light Vaccine: are similar to those of Sputnik V; they are as follows:

  • mild pain at the injection site,
  • fever,
  • headaches,
  • fatigue, and
  • muscle aches.

6. CoronaVac:

CoronaVac, previously called PiCoVacc is the Vaccine developed by Sinovac Biotech China-based Biotechnology Company. It is a formalin-inactivated and alum-adjuvanted vaccine.

DOSAGE:- It is administered in two doses with 14-28 days of the waiting period.

EFFICIENCY:- The evaluation of the EUL according to the WHO’s analysis the CoronaVac Vaccine is 51 % efficient in preventing symptomatic and severe COVID-19 patients and hospitalization and in 100% efficient in vaccinated.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Albania
  2. Armenia
  3. Azerbaijan
  4. Bangladesh
  5. Bolivia
  6. Bosnia and Herzegovina
  7. Botswana
  8. Brazil
  9. Cambodia
  10. China
  11. Chile
  12. Colombia
  13. Dominican Republic
  14. Ecuador
  15. Egypt
  16. Georgia
  17. Hong Kong
  18. Indonesia
  19. Kazakhstan
  20. Laos
  21. Libya
  22. Malaysia
  23. Mexico
  24. Moldova
  25. Nepal
  26. Pakistan
  27. Panama
  28. Paraguay
  29. Philippines
  30. Singapore
  31. South Africa
  32. Thailand
  33. Timor-Leste
  34. Togo
  35. Tunisia
  36. Turkey
  37. Turkmenistan
  38. Ukraine
  39. Uruguay
  40. Zimbabwe

The side effects of this vaccine are as follows:

  • Injection-site pain,
  • fatigue, diarrhoea, and
  • Muscle pain. 

7. EpiVacCorona:

EpiVacCorona - Top 10 COVID-19 Vaccines in the World

The Vaccine developed by the Federal Budgetary Research Institution State Research Center of Virology and Biotechnology in Russia. It is a peptide-based Vaccine for COVID-19 called EpiVacCorona.

DOSAGE:- This Vaccine is injected intramuscularly in two shots between 21-28 days apart.

EFFICIENCY:- According to the sayings of The head of the zoonotic diseases and flu department with the Russian State Research Center of Virology and Biotechnology Vector, the EpiVacCorona Vaccine is efficient in generating immunity after a month of vaccination in the candidates but the official data of trials is yet to be released.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Belarus
  2. Russia
  3. Turkmenistan

The side effects of this EpiVacCorona Vaccine are not any as of now but, common ones are similar for every COVID-19 Vaccines.

8. Covaxin (BBV152):

Covaxin BBV152 is the first inactivated Vaccine of India developed jointly by Bharat Biotech and the National Institute of Virology of India. For International markets US and Canada, A US-based Company, Ocugen, is teaming with Bharat Biotech as a co-developer for Covaxin. The adjuvant of this Covaxin was produced by ViroVax in association with the Adjutant Development Program of NIAID’s.

DOSAGE:- The Covaxin is administered in the deltoid muscle of the upper arm in two doses with a gap of four weeks.

EFFICIENCY:- According to the Ocugen’s words, the Covaxin has an efficacy of 77.8% and is 93.4 % efficient in preventing severe COVID-19 in the phase 3 candidates. Whereas ICMR and Bharat Biotech said that the Covaxin is 78% efficient overall and is 100% effective against the severe COVID-19 after the results of the phase 3 trial candidates in April.

The countries that permitted the approval of use of this vaccine are listed as follows:  

  1. Botswana
  2. Estonia
  3. Guatemala
  4. Guyana
  5. India
  6. Iran
  7. Mauritius
  8. Mexico
  9. Myanmar
  10. Nepal
  11. Paraguay
  12. Philippines
  13. Venezuela
  14. Zimbabwe

The side effects associated with the Covaxin are as follows:

  • Pain,
  • swelling,
  • redness, and
  • itching at the injection site,
  • as well as body ache,
  • weakness,
  • stiffness,
  • nausea,
  • vomiting,
  • fever,
  • malaise, and
  • headache.

9. CoviVac:

CoviVac - Top 10 COVID-19 Vaccines in the World

CoviVac is another Vaccine developed by Russia. It is an inactivated COVID-19 Vaccine manufactured by the Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products. Till now, only Russia has approved the use of this CoviVac Vaccine.

DOSAGE:- The CoviVac Vaccine is delivered as intramuscular injections in two doses within 28 days of gap.

EFFICIENCY:- This Vaccine was approved for its use on 20th February in Russia, the trial results are yet to be disclosed.

No adverse side effects are seen under this Vaccine but the common symptoms are the same as every other COVID Vaccine.

10. Soberana 02:

Soberana 02 - Top 10 COVID-19 Vaccines in the World

Soberana is a Conjugate type of Vaccine developed by the Finlay Institute of Vaccines in Cuba. For its phase 2 and 3 trials, The Pasteur Institute of Iran has also helped her.

DOSAGE:- This Vaccine is given in two doses within 28 days period.

The countries Cuba and Iran approved the use of the Soberana 02 Vaccine.

EFFICIENCY:- The readings of the BioCubaFarma states that the Soberana vaccine’s efficacy is 91.2% recorded in Finlay.

The common side effects of the Soberana 02 Vaccine include injection

  • site pain,
  • inflammation at the injection site, and
  • general discomfort.

But remember only vaccination can take control of this pandemic and will make our lives like before. So, everyone should be vaccinated without fail and win this fight together to save us. 

“THE DELTA VARIANT OF COVID-19 IS CLEARLY GOING TO BE THE THIRD WAVE. IF YOU DECIDE TO NOT GET VACCINATED, THE VIRUS WILL STILL FIND YOU”.

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Author: saigree_admin

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